The aim of this study was to identify the factors that influence the use of Lippia multiflora or knowledge about it. The study showed that L. multiflora is sold more by women than by men (159 people versus 41); The leaf and the stem are the two most used organs, while the decoction is the most used pharmaceutical form; This plant treats 18 diseases, of which cough is the most credible; Young people (18-35 years old) have very little knowledge about the ethno-medical importance of L. multiflora; The Pende and Yansi socio-cultural groups are more familiar with L. multiflora than other ethnic groups (IGKPAC ? 3.80%); L. multiflora is moderately vulnerable in its natural habitat. Given its ethno-medical importance for the population and its scientifically validated pharmacological properties, it is desirable to develop sustainable strategies for the conservation of this species. One option to be explored is its domestication for use as a material for the manufacture of phyto-medical products. Thus, the cultivation of L. multiflora in agroecosystems in forest and savannah environments of the DRC is in progress.

Keywords: Lippia multiflora, endogenous knowledge, degree of threat, conservation, Democratic Republic of the Congo